Cayuse Holdings is a tribally owned, 100% Native American owned economic enterprise founded in 2006. It delivers information technology services, management solutions and technology operations to government, commercial and tribal clients. The firm holds SBA 8(a) status and traces its origins to Cayuse Technologies, a business unit established through a strategic alliance with the Confederated Tribes of the Umatilla Indian Reservation and global industry partners.
Work is organised across four units. Cayuse Government Operations serves government clients; Cayuse Commercial Services serves commercial clients; Cayuse Native Solutions serves native communities; and Cayuse Technologies is the original founding unit. Technical domains covered include information technology services, management solutions, technology operations and government services. The leadership team blends experience across technology, operations and government services.
The company is headquartered near Pendleton, Oregon, with additional offices in the Washington DC/Virginia metro area and Honolulu, Hawaii, and a delivery footprint in Makati City, Philippines. It states a focus on integrity, inclusion and innovation, long-term client relationships, and measurable outcomes and mission-driven impact.






